発表論文、総説等 (Chemical Biology group)
2024
J Biol Chem. (2024), just accepted, https://doi.org/10.1016/j.jbc.2024.105728
2023
1) Zetryana Puteri Tachrim*, Manami Hashinoki, Zeping Wang, Zhang Wen, Zhuang Zihan, Makoto Hashimoto*
Mild and selective hydrogen–deuterium exchange for aromatic hydrogen of amines,
J Label Compd Radiopharm., 66(10), 321‐331 (2023); https://doi.org/10.1002/jlcr.4048
2) Wen Zhang, Kazu Sunami, Shuo Liu, Zihan Zhuang, Yasuko Sakihama, Da-Yang Zhou, Takeyuki Suzuki, Yuta Murai*, Makoto Hashimoto*, Yasuyuki Hashidoko
Accumulation of squalene in filamentous fungi Trichoderma virens PS1-7 in the presence of butenafine hydrochloride, squalene epoxidase inhibitor. -Biosynthesis of 13C-enriched squalene
Bioscience, Biotechnology, and Biochemistry, 87 (10) 1129-1138 (2023); https://doi.org/10.1093/bbb/zbad102
Prof. Dr. Hashidokoから引き継いだ微生物を利用した有用産物の産生に関する初めての論文
3) Hiroko Ikushiro, Taiki Murakami, Aya Takahashi, Asuka Katayama, Taiki Sawai, Haruna Goto, Sajeer Koolath, Yuta Murai, Kenji Monde, Ikuko Miyahara, Nobuo Kamiya, Takato Yano
Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum
J Biol Chem., 299(5) 104684 (2023); https://doi.org/10.1016/j.jbc.2023.104684
4) Sajeer Koolath, Yuta Murai*, Tomoya Suzuki, Mahadeva M. M. Swamy, Seigo Usuki, Kenji Monde
Stereochemistry of sphingolipids in ganglioside GM3 enhances recovery of nervous functionality
ACS Med Chem Lett., (2023); https://doi.org/10.1021/acsmedchemlett.3c00252
Review
1) Yuta Murai*, and Makoto Hashimoto*,
Heteroaromatic diazirines are essential building blocks for material and medicinal chemistry,
Molecules, 28(3), 1408 (2023); https://doi.org/10.3390/molecules28031408
2022
1) Yuta Murai,* Takuma Yoshida, Zetryana Puteri Tachrim, and Makoto Hashimoto*
Design and synthesis of 1,3-bis(3-(trifluoromethyl)diazirin-3-yl)phenylalanine for efficient photo cross-linking,
Heterocycles, 104, 167-177 (2022); DOI: 10.3987/COM-21-14563
2) Zeping Wang, Shoko Ishikawa, Fumina Ohashi, Reo Sagisaka, Yuta Murai, Zetryana Puteri Tachrim, Takeyuki Suzuki, and Makoto Hashimoto*, Novel synthesis and properties of optically pure N-trifluoroacetyl phenylglycine hydroxysuccinimide ester,
Heterocycles, 105, 406 - 416 (2022); DOI : 10.3987/COM-22-S(R)11
3) Wen Zhang, Zetryana Puteri Tachrim, Yurika Tokoro, Zeping Wang, Shoko Ishikawa, Yuta Muraia, Takeyuki Suzuki, and Makoto Hashimoto*,
Hydrogen-deuterium exchange of indole-3-propionic acid with deuterated trifluoromethanesulfonic acid,
Arkivoc, 2022 (ix), 33-39 (2022),
DOI: https://doi.org/10.24820/ark.5550190.p011.836
4) Yu Lin, Hao Wu, Ziang Liu, Jin Li, Rui Cai, Makoto Hashimoto*, and Lei Wang*
Additive-Free Aerobic Oxidation of Hydroazobenzenes: Access to Azobenzenes and Epoxidation of Enones,
Tetrahedron Letters, 108, 154132 (2022).
https://doi.org/10.1016/j.tetlet.2022.154132
2021
1) Manami Hashinoki, Natsumi Kurokawa, Yuta Murai, Zetryana Puteri Tachrim, Yasuko Sakihama, Takeyuki Suzuki, and Makoto Hashimoto*, Synthesis of trifluoromethyldiazirinyl phenylboronic acid derivatives for photoaffinity labeling, Heterocycles, 103, 392-402 (2021); DOI: 10.3987/COM-20-S(K)23
Review
1) Zetryana Puteri Tachrim*, Lei Wang, Yuta Murai, Makoto Hashimoto*, New Trends in Diaziridines Formation and Transformation (A Review), Molecules, , 26, 4496 (2021); https://www.mdpi.com/1420-3049/26/15/4496/pdf
2) Makoto Hashimoto*, Tomoya Nakagita, Takumi Misaka, Recent progress in the use of diaziridine-based sweetener derivatives to elucidate the chemoreception mechanism of the sweet taste receptor, RSC Advances, 11, 32236-32247 (2021); https://pubs.rsc.org/en/content/articlelanding/2021/ra/d1ra04831g
続けてきた甘味受容体ー甘味物質相互作用に光アフィニティーラベルを利用するための基質合成ならびにその生理活性に関するinvited review
2020
1) Zetryana Puteri Tachrim, Natsumi Kurokawa, Yurika Tokoro, and Makoto Hashimoto*
Hydrogen-deuterium exchange of histidine and histamine with deuterated trifluoromethanesulfonic acid.
Heterocycles, 101, 357-362 (2020); DOI: 10.3987/COM-19-S(F)28
2) Tomoya Nakagita, Akiko Ishida, Zetryana Puteri Tachrim, Lei Wang, Takumi Misaka and Makoto Hashimoto*
Asymmetric synthesis of photophore-containing lactisole derivatives to elucidate sweet taste receptors
Molecules, 25, 2790 (2020); doi:10.3390/molecules25122790
3) Zetryana Puteri Tachrim, Kazuhiro Oida, Fumina Ohashi, Natsumi Kurokawa, Lei Wang, Takeyuki Suzuki, and Makoto Hashimoto*, Synthesis of TFA-protected α-Amino Acid Chloride via a Vilsmeier Reagent for Friedel–Crafts acylation
Lett. Org. Chem., 17, 645 - 653 (2020); DOI : 10.2174/1570178617666200207111127
2019
1) Natsumi Kurokawa, Yurika Tokoro, Zetryana Puteri Tachrim, Haruna Wakasa, Yasuko Sakihama, Yasuyuki Hashidoko, and Makoto Hashimoto*, Synthesis of chiral N-trifluoroacetyl-methionine derivatives and applying them as acyl donors for Friedel-Crafts acylation, Arkivoc, (5), 42 – 49 (2019); DOI: https://doi.org/10.24820/ark.5550190.p010.815
2) Zetryana Puteri Tachrim, Shiori Nakagawa, Tadashi Nakamura, Fumina Ohashi, Natsumi Kurokawa, Haruna Wakasa, Yurika Tokoro, Yasuko Sakihama, Yasuyuki Hashidoko, Takeyuki Suzuki, Makoto Hashimoto*, Synthesis of deuterated cyclodopa with hydrogen/deuterium exchange, Heterocycles, 99, 404-414 (2019); DOI: 10.3987/COM-18-S(F)33
3) Tomoya Nakagita, Akiko Ishida, Takumi Matsuya, Takuya Kobayashi, Masataka Narukawa, Takatsugu Hirokawa, Makoto Hashimoto, Takumi Misaka, Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor, PLoS ONE 14(3): e0213552 (2019); https://doi.org/10.1371/journal.pone.0213552
Books chapter
Makoto Hashimoto*, 00111.Diaziridines and diazirines
In Three-membered Heterocycles, and all Fused Systems with a Three-membered Heterocyclic Ring
Comprehensive Heterocyclic Chemistry IV (Reference Module in Chemistry, Molecular Sciences and Chemical Engineering 2019, 1-16 (2019); https://doi.org/10.1016/B978-0-12-409547-2.14763-8
芳香族から脂肪族ジアジリンまでの合成を網羅したinvited 二次資料
2018
1) Shiori Nakagawa, Zetryana Puteri Tachrim, Natsumi Kurokawa, Fumina Ohashi, Yasuko Sakihama, Takeyuki Suzuki, Yasuyuki Hashidoko, Makoto Hashimoto*, pH Stability and Antioxidant Power of CycloDOPA and Its Derivatives
Molecules 2018, 23(8), 1943; https://doi.org/10.3390/molecules23081943
2) Lei Wang, Zetryana Puteri Tachrim, Natsumi Kurokawa, Fumina Ohashi, Haruna Wakasa, Yasuko Sakihama, Yasuyuki Hashidoko, Takeyuki Suzuki, and Makoto Hashimoto*, Optimization of sucrose 1’-position modification with 3-(trifluoromethyl)diazirinyl benzylbromide derivatives for photoaffinity labeling, Arkivoc, (7) 58-65 (2018); https://doi.org/10.24820/ark.5550190.p010.668
3) Zetryana Puteri Tachrim, Tadashi Nakamura, Yasuko Sakihama, Yasuyuki Hashidoko, and Makoto Hashimoto
Application of Appel reaction to the primary alcohol groups of fructooligosaccharides: Synthesis of 6,6’,6’’-trihalogenated 1-kestose derivatives, Arkivoc, (7) 341-348 (2018); DOI: https://doi.org/10.24820/ark.5550190.p010.706ı
4) Zetryana Puteri Tachrim, Kazuhiro Oida, Fumina Ohashi, Haruna Wakasa, Haruka Ikemoto, Natsumi Kurokawa, Yasuko Sakihama, Yasuyuki Hashidoko, Takeyuki Suzuki, Makoto Hashimoto*, TFA-protected α-amino acid N-hydroxysuccinimide ester: Application for inter- and intramolecular acylation, Heterocycles, 97, 877 - 893 (2018); DOI: 10.3987/COM-18-S(T)65
2017
1) Lei Wang, Akiko Ishida, Yasuyuki Hashidoko, Makoto Hashimoto*, Dehydrogenation of NH-NH Bond Triggered by Potassium t-Butoxide in Liquid NH3, Angew. Chem. Int. Ed., 56, 870-873 (2017), German Ed: Angew. Chem., 129, 888 – 891(2017); DOI: 10.1002/anie.201610371
2) Akiko Ishida, Lei Wang, Zetryana Puteri Tachrim, Takeyuki Suzuki, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*, Comprehensive Synthesis of Photoreactive Phenylthiourea Derivatives for the Photoaffinity Labeling
ChemistrySelect, 2, 160-164 (2017); DOI: 10.1002/slct.201601675
3) Makoto Hashimoto,* Takuma Yoshida, Zetryana Puteri Tachrim, YasukoSakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Yuichi Kanaoka, Synthesis of Photophore and Fluorophore Modified OBenzylserine Derivatives
Heterocycles, 95, 462-473 (2017), DOI: 10.3987/COM-16-S(S)37
4) Lei Wang, Zetryana Puteri Tachrim Natsumi Kurokawa, Fumina Ohashi, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*, Base-Mediated One-Pot Synthesis of Aliphatic Diazirines for Photoaffinity Labeling
Molecules, 22, 1389 (2017); doi:10.3390/molecules22081389
5) Zetryana Puteri Tachrim, Kazuhiro Oida, Haruka Ikemoto, Fumina Ohashi, Natsumi Kurokawa, Kento Hayashi, Mami Shikanai, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*, Synthesis of Chiral a-Amino Aryl-Ketone Derivatives with Friedel–Crafts Acylation of a-Amino Acid N-Hydroxysuccinimide Ester, Molecules, 22, 1748 (2017)
doi:10.3390/molecules22101748
Review
1) Zetryana Puteri Tachrim, Lei Wang, Yuta Murai, Takuma Yoshida, Natsumi Kurokawa, Fumina Ohashi, Yasuyuki Hashidoko, Makoto Hashimoto*, Triflouromethanesulfonic Acid as Acylation Catalyst: Special Feature for C- and/or O-Acylation Reactions, Catalysts, 7(2), 40 (2017); doi:10.3390/catal7020040
Books Editors
Hatanaka Y., Hashimoto M. (eds) Photoaffinity Labeling for Structural Probing Within Protein. Springer, Tokyo (2017)
https://doi.org/10.1007/978-4-431-56569-7, Publisher Name Springer, Tokyo
Print ISBN 978-4-431-56568-0 Online ISBN 978-4-431-56569-7, eBook Packages Biomedical and Life Sciences
Books chapter contributions
1) Hashimoto M. (2017) Multifunctional Photoprobes for Identification of Ligand Sites Within Biomolecules.
In: Hatanaka Y., Hashimoto M. (eds) Photoaffinity Labeling for Structural Probing Within Protein. Springer, Tokyo
pp. 1-11; DOI https://doi.org/10.1007/978-4-431-56569-7_1
2) Murai Y., Wang L., Hashimoto M. (2017) Synthesis of Diazirinyl Photophore and Optically Pure Diazirinylphenylalanines for Photoaffinity Labeling. In: Hatanaka Y., Hashimoto M. (eds) Photoaffinity Labeling for Structural Probing Within Protein. Springer, Tokyo, pp. 111-128; DOI https://doi.org/10.1007/978-4-431-56569-7_6
2016
1) Zetryana Puteri Tachrim, Lei Wang, Takuma Yoshida, Miho Muto, Tadashi Nakamura, Katsuyoshi Masuda, Yasuyuki Hashidoko, Makoto Hashimoto*, Comprehensive structural analysis of halogenated sucrose derivatives: Revisiting the reactivity of sucrose primary alcohols, ChemistrySelect, 1, 58-62 (2016); DOI: 10.1002/slct.201500003
2) Yuta Murai*, Takuma Yoshida, Lei Wang, Katsuyoshi Masuda, Yasuyuki Hashidoko, Kenji Monde, Yasumaru Hatanaka, Makoto Hashimoto*, Efficient synthesis of photoreactive 2-propoxyaniline derivatives as artificial sweeteners,
Synlett, 27, 946-950 (2016); DOI: 10.1055/s-0035-1561275
3) Lei Wang, Yasuyuki Hashidoko, Makoto Hashimoto, Cosolvent-Promoted O-Benzylation with Silver(I) Oxide: Synthesis of 1′-Benzylated Sucrose Derivatives, Mechanistic Studies, and Scope Investigation, J. Org. Chem., 2016, 81, 4464–4474; DOI: 10.1021/acs.joc.6b00144
4) Takuma Yoshida, Yasuyuki Hashidoko, Makoto Hashimoto*, Synthesis of benzophenone and phenylazide derivatives of salicin for functional analysis of the bitter taste receptor using photoaffinity labeling, Heterocycles, 93, 355-361 (2016); DOI: 10.3987/COM-15-S(T)4
2015
1) Munenori Sakurai, Takuma Yoshida, Lei Wang, Yuta Murai, Katsuyoshi Masuda, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Synthesis of photoreactive diazirinyl salicin derivative to elucidate functional analysis of the bitter taste receptor, Heterocycles, 90, 698-705 (2015); DOI: 10.3987/COM-14-S(K)36
2) Lei Wang, Yuta Murai, Takuma Yoshida, Akiko Ishida, Katsuyoshi Masuda, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Alternative one-pot synthesis of (trifluoromethyl)phenyldiazirines from tosyloxime derivatives: Application for new synthesis of optically pure diazirinylphenylalanines for photoaffinity labeling,
Org. Lett., 17, 616-619 (2015). DOI: 10.1021/ol503630z
3) Lei Wang, Takuma Yoshida, Yasuyuki Muto, Yuta Murai, Zetryana Puteri Tachrim, Akiko Ishida, Shiori Nakagawa, Yasuko Sakihama, Yasuyuki Hashidoko, Katsuyoshi Masuda, Yasumaru Hatanaka, Makoto Hashimoto*,
Synthesis of diazirine based photoreactive saccharin derivatives for the photoaffinity labeling of gustatory receptors., Eur. J. Org. Chem., 3129–3134 (2015). DOI: 10.1002/ejoc.201500184
4) Takuma Yoshida, Lei Wang, Shiori Nakagawa, Zetryana Puteri Tachrim, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*, Synthesis of Cross-linkable 2,5-Diketopiperazine Derivatives., Lett. Org. Chem., 12 (8), 544-548 (2015). DOI: 10.2174/1570178612666150629181357
2014
1) Munenori Sakurai, Katsuyoshi Masuda, Lei Wang, Yuta Murai, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Synthesis of Methoxy-Substituted Diazirinyl Phenylalanine – A Novel Photoreactive Aspartame Derivative for Functional Analysis of Sweet Receptors, Heterocycles, 88, 629-637 (2014).
2) Lei Wang, Takuma Yoshida, Masashi Okamoto, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*,
2,3-Bis(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)oxirane, Molbank, 2014(1), M816; doi:10.3390/M816 (2014).
3) Lei Wang, Yuta Murai, Takuma Yoshida, Masashi Okamoto, Katsuyoshi Masuda, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Hydrogen-Deuterium Exchange of Cross-Linkable α-Amino Acid Derivatives in Deuterated Triflic Acid, Biosci. Biotechnol. Biochem., 78, 1129-1134 (2014). DOI:10.1080/09168451.2014.917267
4) Makoto Hashimoto*, Yuta Murai, Synthesis of photoreactive aromatic a-amino acids and effective hydrogen-deuterium exchange for aromatic a-amino acids, (光反応性芳香族α−アミノ酸誘導体の合成と芳香族α−アミノ酸を標的とした効率的水素—重水素交換反応), J. Syn. Org. Chem. Jpn., 72, 360-369 (2014)
Review
1) Lei Wang, Yuta Murai, Takuma Yoshida, Masashi Okamoto, Zetryana Puteri Tachrim, Yasuyuki Hashidoko, Makoto Hashimoto*, Utilization of acidic a-amino acids as acyl donors: an effective stereocontrollable synthesis of aryl-keto α-amino acids and their derivatives, Molecules, 19(5), 6349-6367 (2014); doi:10.3390/molecules19056349.
2) Makoto Hashimoto*, Yuta Murai, Synthesis of photoreactive aromatic a-amino acids and effective hydrogen-deuterium exchange for aromatic α-amino acids, （光反応性芳香族α−アミノ酸誘導体の合成と芳香族α−アミノ酸を標的とした効率的水素—重水素交換反応）, J. Syn. Org. Chem. Jpn., 72, 360-369 (2014)
2013
1) Yuta Murai, Katsuyoshi Masuda, Yui Ogasawara, Lei Wang, Yasuyuki Hashidoko, Yasumaru Hatanaka, So Iwata, Takuya Kobayashi, Makoto Hashimoto*, Synthesis of Photoreactive 2-Phenethylamine Derivatives –Synthesis of Adenosine Derivatives Enabling Functional Analysis of Adenosine Receptors via Photoaffinity Labeling-, Eur. J. Org. Chem., 2428-2433 (2013)
2) Lei Wang, Wataru Hisano, Yuta Murai, Munenori Sakurai, Yasuyuki Muto, Haruka Ikemoto, Masashi Okamoto, Takashi Murotani, Reika Isoda, Dongyeop Kim, Yasuko Sakihama, Irnayuli R. Sitepu, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Distinct Metabolites for Photoreactive L-Phenylalanine Derivatives in Klebsiella sp. CK6 Isolated from Rhizosphere of a Wild Dipterocarp Sapling, Molecules, 18, 8393-8401 (2013) (doi:10.3390/molecules18078393, special issue: Reagents and Methods for Protein Target Identification)
3) Yuta Murai, Lei Wang, Katsuyoshi Masuda, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Rapid and Controllable Hydrogen-deuterium Exchange on Aromatic Rings of a-Amino Acids and Peptides, Eur. J. Org. Chem., 5111–5116 (2013).
4) Yuta Murai, Lei Wang, Yasuyuki Muto, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*,
Simple and Stereocontrolled Preparation of Benzoylated Phenylalanine Using Friedel–Crafts Reaction in Trifluoromethanesulfonic Acid for Photoaffinity Labeling, Heterocycles, 87, 2119-2126 (2013).
2012
1) Yuka Tsunekawa, Katsuyoshi Masuda, Miho Muto, Yasuyuki Muto, Yuta Murai, Yasuyuki Hashidoko, Yoshitake Orikasa, Yuji Oda, Yasumaru Hatanaka, and Makoto Hashimoto*, Chemo-enzymatic synthesis of 1’- photoreactive sucrose derivatives via ether linkage, Heterocycles, 84, 283-290 (2012).
2) Yuta Murai, Katsuyoshi Masuda, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, Makoto Hashimoto*, Comprehensive Synthesis of Photoreactive (3-Trifluoromethyl)diazirinyl Indole Derivatives from 5- and 6- Trifluoroacetylindoles for Photoaffinity Labeling, J. Org. Chem., 77, 8581-8587 (2012). dx.doi.org/10.1021/jo301552m
3) Yasuyuki Muto, Yuta Murai, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*,
Effective Friedel-Crafts Acylation of Biotin Acid Chloride in Trifluoromethanesulfonic Acid.,
Biosci. Biotechnol. Biochem., 76, 2162-2164 (2012).
4) Yui Ogasawara, Yuta Murai, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto*,
Quantitative analysis of Cu(I) concentration in click chemistry —biotinylation at side chain of propargylglycine using click chemistry under heating conditions —, Heterocycles, 86, 735-743 (2012).
2011
1) Ryo Murashige, Yuka Hayashi, Syo Ohmori, Ayuko Torii, Yoko Aizu, Yasuyuki Muto, Yuta Murai, Yuji Oda, Makoto Hashimoto*, Comparisons of O-acylation and Friedel-Crafts acylation of phenols and acyl chlorides and Fries rearrangement of phenyl esters in trifluoromethanesulfonic acid: Effective synthesis of optically active homotyrosines, Tetrahedron, 67, 641-649 (2011)
2) Yuta Murai, Yasuyuki Hashidoko, Makoto Hashimoto*, Novel synthesis of optically active bishomotyrosine derivatives using the Friedel-Crafts reaction in triflic acid, Biosci. Biotechnol. Biochem., 75, 352-354 (2011).
2010
1) Katsuyoshi Masuda, Ayako Koizumi, Takumi Misaka, Yasumaru Hatanaka, Keiko Abe, Takaharu Tanaka, Masaji Ishiguro, Makoto Hashimoto*, Photoactive ligands probing the sweet taste receptor. Design and synthesis of highly potent diazirinyl D-phenylalanine derivatives, Bioorg. Med. Chem. Lett., 20, 1081-1083 (2010).
2) Makoto Hashimoto*, Keitaro Furukawa, Takenori Tomohiro, Yasumaru Hatanaka, Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components, Chem. Pharm. Bull., 58, 405-407 (2010)
3) Yuta Murai, Miho Takahashi, Yasuyuki Muto, Yasumaru Hatanaka, Makoto Hashimoto*, Simple deuterium introduction at α-position of carbonyl in diazirinyl derivatives for photoaffinity labeling, Heterocycles, 82, 909-915 (2010).
2009
1) Makoto Hashimoto*, Miho Takahashi, Effective Friedel-Crafts acylations of O- and C- aryl glycosides with triflic acid, Heterocycles, 77, 227-231 (2009).
2) Yuta Murai, Yasumaru Hatanaka, Yuichhi Kanaoka, Makoto Hashimoto*, Effective synthesis of opticaly active 3-phenyl-3- (3-trifluoromethyl) diazirinyl bishomophenylalanine derivatives, Heterocycles, 79, 359-364 (2009)
3) Ryo Murashige, Yuta Murai, Yasumaru Hatanaka, Makoto Hashimoto*, Effective synthesis of optically active trifluoromethyldiazirinyl homophenylalanine and aroylalanine derivatives with Friedel-Crafts reactions in triflic acid, Biosci. Biotechnol. Biochem.,73, 1377-1380 (2009).
2008
1) Makoto Hashimoto*, Yasumaru Hatanaka, A novel biotinyl and diazirinyl ceramide analogue for photoaffinity labeling, Bioorg. Med. Chem. Lett., 18, 650-652 (2008).
2) Ryo Murashige, Yuka Hayashi, Makoto Hashimoto*, Asymmetric and efficient synthesis of homophenyl- alanine derivatives via Friedel-Crafts reaction with trifluoromethanesulfonic acid, Tetrahedron Lett., 49, 6566-6568 (2008).
Review
1) Makoto Hashimoto*, Yasumaru Hatanaka, Recent Progress in Diazirine-Based Photoaffinity Labeling,
Eur. J. Org. Chem., 2513-2523 (2008)
ジアジリン系光アフィニティーラベルのinvited reviewとして最も引用されている物の一つ
2007
1) Makoto Hashimoto*, Yuhi Kato, Yasumaru Hatanaka, Selective hydrogenation of alkene in (3-trifluoromethyl) phenyldiazirine photophor with Wilkinson’s catalyst for photoaffinity labeling, Chem. Pharm. Bull., 55, 1540-1543 (2007).
2006
1) Makoto Hashimoto*, Yasumaru Hatanaka, Practical conditions for photoaffinity labeling with 3-trifluoromethyl-3-phenyldiazirine photophore, Anal. Biochem., 348, 154-156 (2006)
2) Makoto Hashimoto*, Yuhi Kato, Yasumaru Hatanaka, Simple method for the introduction of iodo-label on (3-trifluoromethyl) phenyldiazirine for photoaffinity labeling, Tetrahedron Lett., 47, 3391-3394 (2006)
3) Hiroyuki Nakashima, Makoto Hashimoto, Yutaka Sadakane, Takenori Tomohiro, Yasumaru Hatanaka, Simple and Versatile Method for Tagging Phenyldiazirine Photophores, J. Am. Chem. Soc., 128, 15092-15093 (2006)
4) Makoto Hashimoto*, Yasumaru Hatanaka, Positively coded photoaffinity label for altering isoelectric points of proteins, Bioorg. Med. Chem. Lett., 16, 5998-6000 (2006)
2005
1) Makoto Hashimoto*, T. Komano, K. Nabeta, Yasumaru Hatanaka, Stereoselective synthesis of (E)- and (Z)-beta-bromostyrene containing trifluoromethyldiazirine for photoaffinity labeling, Chem. Pharm. Bull., 53, 140-142 (2005)
2) Makoto Hashimoto*, Yasumaru Hatanaka, Post-biotinylation of photocrosslinking by Staudinger-Bertozzi ligation of preinstalled alkylazide tag, Chem. Pharm. Bull., 53, 1510-1512 (2005)
3) Makoto Hashimoto*, Yasumaru Hatanaka, Diol derivative of 3-trifluoromethyl phenyldiazirine for post-labeling of photocrosslink, Heterocycles, 66, 531-534 (2005)
Review
1) Tomohiro Tomohiro, Makoto Hashimoto, Yasumaru Hatanaka, Cross-Linking Chemistry and Biology: Development of Multifunctional Photoaffinity Probes, Chem. Record, 5, 385-395 (2005).